Dyxy

Cyclosporine Dosage

Ciclosporina ahumada family

An Introduction to Your Cyclosporine Dosage. The dose of cyclosporine ( Gengraf, Neoral, Sandimmune ) your healthcare provider recommends will vary, depending on a number of factors, including: The particular cyclosporine product you are using. The reason you are using the medicine. How you respond to it Your weight Your cyclosporine blood levels. Other medications you are taking. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so. The usual initial dosage of cyclosporine IV injection is 5 mg to 6 mg per kg (2.3 mg to 2.7 mg per pound) given over two to six hours. This amount is usually continued until you are able to take cyclosporine by mouth. When used to prevent organ transplant rejection, cyclosporine is always used in combination with a corticosteroid medicine, such as prednisone. You will be started on a high corticosteroid dose, which will be gradually reduced over a couple of months to a lower maintenance dose. Children are generally started on the same cyclosporine doses (based on weight) as adults. However, some children may actually need higher dosages on a mg-per-pound basis. If you are unable to take cyclosporine by mouth, you may be given the medicine as an intravenous. Cyclosporine Dosing for the Prevention of Transplant Rejection. The recommended initial dosage of regular (unmodified) cyclosporine capsules and oral solution (Sandimmune) to help prevent an organ transplant rejection is 15 mg per kg (6.8 mg per pound) given 4 to 12 hours before transplantation. The maintenance dosage may be as low as 3 mg per kg (1.4 mg per pound) in people who have had a kidney transplant. For modified cyclosporine (Neoral, Gengraf the initial dosage for preventing organ rejection is individualized based on your weight, your transplant.

“The initial dosage is usually continued for one to two weeks, and then gradually decreased by 5 percent each week to a maintenance dosage of 5 mg to 10 mg per kg per day (2.3 mg to 4.5 mg per pound).”
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Initial doses may be as low as 10 mg to 14 mg per kg per day (4.5 mg to 6.4 mg per pound) in some people who have received a kidney transplant.
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Ciclosporina ahumada family
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